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toremifen binder sig specifikt til østrogenreceptorer, kompetitivt med estradiol, og hæmmer den østrogeninducerede stimulation af dna syntesen og cellereplikationen.
toremifene binds specifically to estrogen receptors, competitively with oestradiol, and inhibits estrogen- induced stimulation of dna synthesis and cell replication.
Last Update: 2017-04-26
Usage Frequency: 3
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begrænsede kliniske data tyder på at raloxifen kan være forbundet med en mærkbar øgning i serum- triglycerid hos patienter der tidligere har haft oral østrogeninduceret hypertriglyceridæmi (>5,6 mmol/l).
limited clinical data suggest that in patients with a history of oral oestrogen-induced hypertriglyceridemia (>5.6 mmol/l), raloxifene may be associated with a marked increase in serum triglycerides.
Last Update: 2017-04-26
Usage Frequency: 5
Quality:
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