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strimvelis bruges til at behandle en alvorlig sygdom kaldet ada-scid (svær kombineret adenosindeaminase-immundefekt).
strimvelis is used to treat a serious condition called ada-scid (adenosine deaminase-severe combined immune deficiency).
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
den primære metabolisering af nelarabin er o-demethylering vha. adenosindeaminase til dannelse af ara-g, som undergår hydrolyse og danner guanin.
the principal route of metabolism for nelarabine is o-demethylation by adenosine deaminase to form ara-g, which undergoes hydrolysis to form guanine.
Last Update: 2017-04-26
Usage Frequency: 4
Quality:
nelarabin demethyleres hurtigt af adenosindeaminase (ada) til ara-g, som derefter phosphoryleres intracellulært af deoxyguanosinkinase og deoxycytidinkinase til dets 5’-monophosphatmetabolit.
nelarabine is rapidly demethylated by adenosine deaminase (ada) to ara-g and then phosphorylated intracellularly by deoxyguanosine kinase and deoxycytidine kinase to its 5’-monophosphate metabolite.
Last Update: 2017-04-26
Usage Frequency: 5
Quality:
autolog cd34+-beriget cellefraktion indeholdende cd34+-celler transduceret med retroviral vektor, som koder for den humane adenosindeaminase (ada)- cdna-sekvens
autologous cd34+ enriched cell fraction that contains cd34+ cells transduced with retroviral vector that encodes for the human ada cdna sequence
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
ada-scid er en sjælden, arvelig sygdom, hvor der sker en ændring (mutation) i det gen, der er nødvendigt for at lave det såkaldte adenosindeaminase-enzym (ada).
ada-scid is a rare inherited condition in which there is a change (mutation) in the gene needed to make an enzyme called adenosine deaminase (ada).
Last Update: 2017-04-26
Usage Frequency: 1
Quality: