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intestinal metaplasi blev også observeret, ligesom leydig cellehyperplasi og benigne leydig celletumorer.
intestinal metaplasia was also observed, as were leydig cell hyperplasia and bening leydig cell tumours.
Last Update: 2012-04-12
Usage Frequency: 5
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karcinogenicitetsstudier med rotter med den racemiske blanding har vist gastrisk ecl-cellehyperplasi og carcinoider.
carcinogenicity studies in the rat with the racemic mixture have shown gastric ecl-cell hyperplasia and carcinoids.
Last Update: 2017-04-26
Usage Frequency: 1
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i et karcinogenstudie udviklede hanrotter leydig- cellehyperplasi og adenomer pga. pramipexols prolaktinhæmmende effekt.
in a carcinogenicity study, male rats developed leydig cell hyperplasia and adenomas, explained by the prolactin-inhibiting effect of pramipexole.
Last Update: 2012-04-12
Usage Frequency: 14
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i carcinogenicitetsundersøgelser hos mus udvikledes dosis- relateret gastrisk ecl cellehyperplasi såvel som levertumorer og adenom af rete testis.
in mouse carcinogenicity studies dose-related gastric ecl cell hyperplasia developed as well as liver tumours and adenoma of rete testis.
Last Update: 2012-04-12
Usage Frequency: 5
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i to carcinogenicitetsundersøgelser på rotter frembragte lansoprazol dosis- relateret gastrisk ecl cellehyperplasi og ecl cellecarcinoider forbundet med hypergastrinæmi grundet hæmning af syresekretion.
in two rat carcinogenicity studies, lansoprazole produced dose-related gastric ecl cell hyperplasia and ecl cell carcinoids associated with hypergastrinaemia due to inhibition of acid secretion.
Last Update: 2012-04-12
Usage Frequency: 5
Quality:
i to undersøgelser over carcinogenicitet hos rotter frembragte lansoprazol dosis- relateret gastrisk ecl cellehyperplasi og ecl cellecarcinoider forbundet med hypergastrinæmi grundet hæmning af syresekretionen og retinal atrofi.
in two rat carcinogenicity studies, lansoprazole produced dose-related gastric ecl cell hyperplasia and ecl cell carcinoids associated with hypergastrinaemia due to inhibition of acid secretion and retinal atrophy.
Last Update: 2012-04-12
Usage Frequency: 4
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i to carcinogenicitetsforsøg med rotter fremkaldte lansoprazol dosisrelateret gastrisk ecl - cellehyperplasi og ecl- cellecarcinoider, der blev forbundet med hypergastrinæmi på grund af hæmningen af syresekretion.
in two rat carcinogenicity studies, lansoprazole produced dose-related gastric ecl cell hyperplasia and ecl cell carcinoids associated with hypergastrinaemia due to inhibition of acid secretion.
Last Update: 2012-04-12
Usage Frequency: 5
Quality:
c-cellehyperplasi og adenomer sås hos rotter og mus uanset dosisniveau og nul-bivirknings-niveauet (noael) kunne ikke defineres.
c-cell hyperplasia and adenoma were seen at all doses in rats and a no observed adverse effect level (noael) could be not defined.
Last Update: 2017-04-26
Usage Frequency: 1
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Ændringer inkluderede øget alaninaminotransferase og alkalifosfataseaktivitet og histopatologiske fund (hovedsageligt sinusoidecelle- eller kupffer-cellehyperplasi/hypertrofi, galdegangshyperplasi og periportal fibrose).
alterations included increased alanine aminotransferase and alkaline phosphatase activity and histopathology findings (mainly sinusoidal cell or kupffer cell hyperplasia/hypertrophy, bile duct hyperplasia and periportal fibrosis).
Last Update: 2017-04-26
Usage Frequency: 4
Quality: