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det er et syntetisk decapeptid med en struktur, der ligner bradykinin, men med 5 ikke-proteinogene aminosyrer.
it is a synthetic decapeptide with a structure similar to bradykinin, but with 5 non-proteinogenic amino acids.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
det aktive lægemiddelstof er et syntetisk decapeptid, som har høj antagonistisk aktivitet med det naturligt forekommende gonadotropinfrigivende hormon (gnrh).
the active substance ganirelix (inn) is a synthetic decapeptide with high antagonistic activity to the naturally occurring gonadotrophin releasing hormone (gnrh).
Last Update: 2017-04-26
Usage Frequency: 4
Quality:
aminosyrerne i positionerne 1, 2, 3, 6, 8 og 10 i det naturlige gnrh decapeptid er erstattet og det endelige molekyle bliver n-ac-d-nal(2)1,d- pc1phe2,d-pal(3)3,d-harg(et2)6,l-harg(et2)8,d-ala10]-gnrh med en molekylevægt på 1570,4.
the amino acids at positions 1, 2, 3, 6, 8 and 10 of the natural gnrh decapeptide have been substituted resulting in n-ac-d-nal(2)1, d-pclphe2, d-pal(3)3, d-harg(et2)6, l-harg(et2)8, d-ala10]-gnrh with a molecular weight of 1570.4.
Last Update: 2017-04-26
Usage Frequency: 4
Quality: