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reversibel binding af ibrutinib til humant plasmaprotein in vitro var 97,3 % uden koncentrationsafhængighed i intervallet 50 til 1.000 ng/ml.
reversible binding of ibrutinib to human plasma protein in vitro was 97.3% with no concentration dependence in the range of 50 to 1,000 ng/ml.
Last Update: 2017-04-26
Usage Frequency: 1
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binding af pazopanib til humant plasmaprotein in vivo var over 99 %, og der var ingen koncentrationsafhængighed i intervallet 10-100 g/ml.
binding of pazopanib to human plasma protein in vivo was greater than 99 % with no concentration dependence over the range of 10-100 g/ml.
Last Update: 2017-04-26
Usage Frequency: 1
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fordeling binding af sunitinib og dets aktive hovedmetabolit til human plasmaprotein er i in vitro undersøgelser henholdsvis 95% og 90%, og der er tilsyneladende ingen koncentrationsafhængighed.
distribution binding of sunitinib and its primary active metabolite to human plasma protein in in vitro assays was 95% and 90%, respectively, with no apparent concentration dependence.
Last Update: 2012-04-12
Usage Frequency: 5
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polyglutamation er en tids- og koncentrationsafhængig proces, som primært finder sted i tumorceller og i mindre grad i normalt væv.
polyglutamation is a time- and concentration-dependent process that occurs in tumour cells and, to a lesser extent, in normal tissues.
Last Update: 2017-04-26
Usage Frequency: 6
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