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det mest almindelige resultat ved studier med gentaget indgift var øget primær spongiosa i rørknoglernes metafyser hos voksende dyr ved næsten alle doser.dette resultat afspejler stoffets farmakologiske antiresorptive aktivitet.
the most frequent finding in the repeat-dose studies consisted of increased primary spongiosa in the metaphyses of long bones in growing animals at nearly all doses, a finding that reflected the compound 's pharmacological antiresorptive activity.