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dyremodeller bekræfter, at ibandronsyre er en højpotent hæmmer af osteoklastaktiviteten.
animal models confirm that ibandronic acid is a highly potent inhibitor of osteoclastic activity.
Last Update: 2017-04-26
Usage Frequency: 9
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osteoklastaktiviteten hæmmes, men dannelse eller binding af osteoklaster påvirkes ikke.
osteoclastic activity is inhibited, but formation and binding of the osteoclasts is not affected.
Last Update: 2012-04-12
Usage Frequency: 3
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ved at hæmme osteoklastaktiviteten via dets specifikke receptorer, nedsætter laksecalcitonin knogleresorptionen.
by inhibiting osteoclast activity via its specific receptors, salmon calcitonin decreases bone resorption.
Last Update: 2017-04-26
Usage Frequency: 6
Quality:
ved at hæmme osteoklastaktiviteten via dets specifikke receptorer, nedsætter lakse calcitonin knogleresorptionen.
by inhibiting osteoclast activity via its specific receptors, human calcitonin decreases bone resorption.
Last Update: 2012-04-12
Usage Frequency: 3
Quality:
ved at hæmme osteoklastaktiviteten via dets specifikke receptorer, nedsætter17/31 calcitonin knogleresorptionen.
by inhibiting osteoclast activity via its specific receptors, calcitoinin decreases bone resorption.
Last Update: 2008-03-04
Usage Frequency: 1
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ibandronsyre hæmmer selektivt osteoklastaktiviteten, reducerer knogleresorptionen og mindsker herved skeletkomplikationerne ved den maligne sygdom.
ibandronic acid selectively inhibits osteoclast activity, reducing bone resorption and thereby reducing skeletal complications of the malignant disease.
Last Update: 2017-04-26
Usage Frequency: 6
Quality:
ibandronsyre er et højpotent bisphosphonat tilhørende gruppen af nitrogenholdige bisphosphonater, som virker selektivt på knoglevæv og specifikt hæmmer osteoklastaktiviteten uden direkte påvirkning af knogleopbygningen.
ibandronic acid is a highly potent bisphosphonate belonging to the nitrogen-containing group of bisphosphonates, which act selectively on bone tissue and specifically inhibit osteoclast activity without directly affecting bone formation.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
bisfosfonaters selektive virkning på knogler er baseret på deres høje affinitet for mineraliseret knogle, men den præcise molekylære mekanisme, der fører til inhibition af osteoklastaktiviteten, er stadig ukendt.
the selective action of bisphosphonates on bone is based on their high affinity for mineralised bone, but the precise molecular mechanism leading to the inhibition of osteoclastic activity is still unclear.
Last Update: 2017-04-26
Usage Frequency: 5
Quality: