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nitisinon er en kompetitiv hæmmer af 4-hydroxyfenylpyruvatdioxygenase, et enzym, der går forud for fumarylacetoacetathydrolase i tyrosinkatabolismens vej.
nitisinone is a competitive inhibitor of 4-hydroxyphenylpyruvate dioxygenase, an enzyme which precedes fumarylacetoacetate hydrolase in the tyrosine catabolic pathway.
Last Update: 2017-04-26
Usage Frequency: 6
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den biokemiske defekt ved arvelig tyrosinæmi type 1 (ht-1) er en mangel på fumarylacetoacetathydrolyase, der er det sidste enzym på tyrosinkatabolismens vej.
the biochemical defect in hereditary tyrosinemia type 1 (ht-1) is a deficiency of fumarylacetoacetate hydrolase, which is the final enzyme of the tyrosine catabolic pathway.
Last Update: 2017-04-26
Usage Frequency: 6
Quality: