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available data suggest that mitotane modifies the peripheral metabolism of steroids and that it also directly suppresses the adrenal cortex.
tilgængelige data antyder, at mitotan modificerer steroiders perifere metabolisme, og at det også direkte undertrykker den adrenale cortex.
data are available to suggest that mitotane modifies the peripheral metabolism of steroids as well as directly suppressing the adrenal cortex.
der foreligger data, der antyder, at mitotan modificerer steroiders perifere metabolisme såvel som direkte supprimering af den adrenale cortex.
the decreased adrenal and thymus weights accompanied by atrophy of the adrenal cortex and lymphoid depletion of the thymus correlated with the decreased cortisol levels, and were consistent with the pharmacologic effects of betamethasone.
den reducerede vægt af binyrer og thymus sammen med atrofi i binyrebarken og lymfoid udtømning af thymus hang sammen med de reducerede kortisolniveauer og svarede til de farmakologiske effekter af betamethason.