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inhibition of osteoclastic bone resorption, which alters the bone marrow microenvironment,
hæmning af osteoklastisk knogleresorption, hvilket ændrer knoglemarvens mikromiljø og
Last Update: 2008-03-04
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in myeloma, bortezomib affects the ability of myeloma cells to interact with the bone marrow microenvironment.
i myelomer påvirker bortezomib myelomcellernes evne til at interagere med knoglemarvens mikromiljø.
Last Update: 2017-04-26
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amphibians are ectothermic. areas of different temperature and humidity are beneficial, to allow amphibians to seek their preferred microenvironment.
padder er vekselvarme og trives med områder med forskellig temperatur og luftfugtighed, så de kan opsøge deres foretrukne mikromiljø.
Last Update: 2014-11-04
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microenvironment, making it less conducive to tumour cell growth, anti-angiogenic activity and anti-pain activity.
og mindsker bidraget til tumorcellevæksten, den anti- angiogenetiske aktivitet og anti- smerte aktiviteten.
Last Update: 2012-04-12
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in vivo: inhibition of osteoclastic bone resorption, which alters the bone marrow microenvironment, making it less conducive to tumour cell growth and anti-angiogenic activity.
in vivo: hæmning af osteoklastisk knogleresorption, hvilket ændrer knoglemarvens mikromiljø og mindsker bidraget til tumorcellevæksten og den anti-angiogenetiske aktivitet.
Last Update: 2017-04-26
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the anti-tumour effect of temsirolimus, therefore, may also in part stem from its ability to depress levels of hif and vegf in the tumour or tumour microenvironment, thereby impairing vessel development.
anti-tumorvirkningen af temsirolimus kan derfor også delvis stamme fra dets evne til at sænke niveauet af hif og vegf i tumor eller tumors mikromiljø og derved svække udviklingen af blodkar.
Last Update: 2017-04-26
Usage Frequency: 4
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through inhibition of chemokine receptors cxcr4 and cxcr5 signalling induced by the chemokines cxcl12 and cxcl13, respectively, idelalisib inhibits homing and retention of malignant b-cells in the tumour microenvironment including lymphoid tissues and the bone marrow.
via hæmning af cxcr4 og cxcr5 kemokinreceptorernes signalering, der induceres af hhv. kemokinerne cxcl12 og cxcl13, hæmmer idelalisib cellemigration til oprindelsestedet og retention af maligne b-celler i tumor-mikromiljøet, herunder lymfatisk væv og i knoglemarven.
Last Update: 2017-04-26
Usage Frequency: 1
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