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anencephaly and unilateral anophthalmia
Ühel lootel leiti anentsefaalia ja unilateraalne anoftalmia koos sekundaarse keele suurenemisega, teisel lootel oli mikrooftalmia ja kolmandal suulaelõhe.
Last Update: 2011-10-23
Usage Frequency: 1
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anencephaly and unilateral anophthalmia with secondary enlargement of the tongue were observed in one foetus, microophthalmia was observed in another foetus and cleft palate was observed in a third foetus.
Ühel lootel leiti anentsefaalia ja unilateraalne anoftalmia koos sekundaarse keele suurenemisega, teisel lootel oli mikrooftalmia ja kolmandal suulaelõhe.
Last Update: 2017-04-26
Usage Frequency: 4
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anencephaly and unilateral anophthalmia with secondary enlargement of the tongue were observed in one foetus, microophthalmia was observed in another foetus, and cleft palate was observed in a third foetus.
26 suurenemisega, teisel lootel oli mikrooftalmia ja kolmandal suulaelõhe.
Last Update: 2011-10-23
Usage Frequency: 3
Quality:
Warning: This alignment may be wrong.
Please delete it you feel so.
anencephaly and unilateral anophthalmia with secondary enlargement of the tongue were observed in one foetus, micro-ophthalmia was observed in another foetus, and cleft palate was observed in a third foetus.
Ühel lootel leiti anentsefaalia ja unilateraalne anoftalmia koos sekundaarse keele suurenemisega, teisel lootel oli mikrooftalmia ja kolmandal suulaelõhe.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
in teratology studies in rats and rabbits, foetal resorptions and malformations occurred in rats at 6 mg kg-1 day-1 (including anophthalmia, agnathia, and hydrocephaly) and in rabbits at 90 mg kg-1 day-1 (including cardiovascular and renal anomalies, such as ectopia cordis and ectopic kidneys, and diaphragmatic and umbilical hernia), in the absence of maternal toxicity.
11 rottidel ja küülikutel teostatud teratogeensusuuringus ilmnesid loote resorptsioon ja arenguhäired rottidel annuste 6 mg/ kg/ ööpäevas (sh anoftalmia, agnaatia ja hüdrotsefaalia) ning küülikutel annuste 90 mg/ kg/ ööpäevas manustamisel (sh südame ja neerude arenguhäired, nt südame ja neerude ektoopia, diafragmaal – ja nabasong).
Last Update: 2012-04-11
Usage Frequency: 4
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