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zonisamide is metabolised primarily through reductive cleavage of the benzisoxazole ring of the parent drug by cyp3a4 to form 2-sulphamoylacetylphenol (smap) and also by n-acetylation.
a zoniszamid metabolizációja elssorban az anyavegyület benzizoxazol-gyrjének reduktív hasítása útján történik, amelyet a cyp3a4 idéz el 2-szulfamoil-acetil-fenol (smap) képzdése közben, valamint n-acetiláció útján.
Last Update: 2008-03-04
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