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pdgfr beta
recettore beta del fattore di crescita pastrino-derivato
Last Update: 2014-12-09
Usage Frequency: 4
Quality:
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pdgfr-alpha
recettore alfa del fattore di crescita piastrino-derivato
Last Update: 2014-12-09
Usage Frequency: 2
Quality:
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pdgfr kit 69 210
pdgfr kit 69 210
Last Update: 2011-10-23
Usage Frequency: 2
Quality:
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leukaemia (cel) with fip1l1-pdgfr rearrangement.
(lec) con riarrangiamento fip1l1-pdgfr.
Last Update: 2008-03-04
Usage Frequency: 4
Quality:
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in 61 of these 117 patients fip1l1-pdgfr fusion kinase was identified.
in 61 di questi 117 pazienti è stata identificata la chinasi di fusione fip1l1-pdgfr.
Last Update: 2008-03-04
Usage Frequency: 4
Quality:
Warning: This alignment may be wrong.
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imatinib inhibits signalling and proliferation of cells driven by dysregulated pdgfr and abl kinase activity.
imatinib inibisce il segnale e la proliferazione di cellule guidate dalla deregolazione del pdgfr e dall’attività chinasica di abl.
Last Update: 2017-04-26
Usage Frequency: 7
Quality:
platelet-derived growth factor receptor (pdgfr) gene re-arrangements.
riarrangiamenti del gene del recettore per il fattore di crescita di origine piastrinica (pdgfr) .
Last Update: 2008-03-04
Usage Frequency: 4
Quality:
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for instance, the tyrosine kinase pdgfr was found to have increased intensity in these tumor cells.
ad esempio è stato trovato che la tirosinkinasi pdgfr presentava una maggiore espressione in queste cellule tumorali.
Last Update: 2018-02-13
Usage Frequency: 1
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myelodysplastic/ myeloproliferative diseases with pdgfr gene re-arrangements could be associated with high eosinophil levels.
le malattie mielodisplastiche/ mieloproliferative con riarrangiamenti del gene pdgfr potrebbero essere associate a livelli elevati di eosinifili.
Last Update: 2012-04-12
Usage Frequency: 6
Quality:
an additional four hes patients were found to be fip1l1-pdgfr-positive in other 3 published reports.
in altri 3 lavori pubblicati, ulteriori quattro pazienti con hes sono risultati positivi per la chinasi di fusione fip1l1-pdgfr.
Last Update: 2008-03-04
Usage Frequency: 4
Quality:
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in addition, in vivo olaratumab has been shown to disrupt the pdgfr-α pathway in tumour cells and inhibit tumour growth.
inoltre, in vivo, olaratumab ha dimostrato di alterare la via di segnale di pdgfr-α nelle cellule tumorali e di inibire la crescita tumorale.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
five (5) patients with mds/mpd associated with pdgfr gene re-arrangements were reported in 4 publications.
cinque (5) pazienti con mds/mpd associata al riarrangiamento del gene pdgfr sono stati riportati in 4 pubblicazioni.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
seventeen (17) patients with gist (with or without kit and pdgfr mutations) were reported in 7 publications.
diciassette (17) pazienti con gist (con o senza mutazioni di kit e pdgfr) sono stati riportati in 7 pubblicazioni.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
at the time of the original analysis, three of the four patients with detected pdgfr gene rearrangements developed haematological response (2 chr and 1 phr).
al tempo dell’analisi originale, tre dei quattro pazienti con riscontro del riarrangiamento del gene pdgfr avevano sviluppato una risposta ematologica (2 chr e 1 phr).
Last Update: 2017-04-26
Usage Frequency: 4
Quality:
the same publication reported long term follow-up data from 12 mds/mpd patients with pdgfr gene rearrangements (5 patients from study b2225).
la stessa pubblicazione ha riportato i dati di follow-up a lungo termine di 12 pazienti (di cui 5 pazienti dello studio b2225) affetti da mds/mpd con riarrangiamenti del gene pdgfr.
Last Update: 2017-04-26
Usage Frequency: 12
Quality:
olaratumab is an antagonist of platelet derived growth factor receptor-α (pdgfr-α), expressed on tumour and stromal cells.
olaratumab è un antagonista del recettore-α del fattore di crescita derivato dalle piastrine (pdgfr-α), espresso sulle cellule tumorali e stromali.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
raf kinases are serine/ threonine kinases, whereas c-kit, flt-3, vegfr-2, vegfr-3, and pdgfr-ß are receptor tyrosine kinases.
le raf chinasi sono serin/ treonin-chinasi, mentre c-kit, flt-3, vegfr-2, vegfr-3 e pdgfr-ß sono tirosin-chinasi del recettore.
Last Update: 2012-04-12
Usage Frequency: 4
Quality: