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inhibition of cyp isoforms
inibizzjoni ta’ isoformi ta’ cyp
Last Update: 2017-04-26
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cyp isoforms selective substrates:
substrati selettivi ta ’ isoformi ta ’ cyp:
Last Update: 2012-04-10
Usage Frequency: 2
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two isoforms, cox-1 and cox-2, have been identified.
Ġew identifikati żewġ iżoforom, cox-1 u cox-2.
Last Update: 2017-04-26
Usage Frequency: 3
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there are two isoforms of cox, cox-1, and cox-2.
hemm żewg isoforms ta ’ cox, cox- 1 u cox- 2.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
Warning: This alignment may be wrong.
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rivaroxaban neither inhibits nor induces any major cyp isoforms like cyp3a4.
rivaroxaban la jinibixxi u lanqas jindotta isoformi maġġuri ta’ cyp bħal cyp3a4.
Last Update: 2017-04-26
Usage Frequency: 3
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it binds with high affinity to the vegf-a isoforms (e.g.
teħel b’affinità kbira ma’ l-iżoformi vegf-a (e.ż.
Last Update: 2017-04-26
Usage Frequency: 3
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the cyclo-oxygenase enzyme (cox) is present in two isoforms.
l-enzima cyclo-oxygenase (cox) hija preżenti f’żewġ isoformi.
Last Update: 2017-04-26
Usage Frequency: 1
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interaction with substrates of cyp 450 isoforms are thus not expected and have not been shown.
għalhekk, interazzjoni ma’ sottostrati ta’ iżoformi ta’ cyp 450 mhumiex mistennija u ma ġewx osservati.
Last Update: 2017-04-26
Usage Frequency: 1
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cyp2d15 and cyp3a12 were identified as the canine isoforms involved in the hepatic biotransformation of maropitant.
cyp2d15 u cyp3a12 kienu identifikati bħala l- forom fil - klieb involuti fil- biotrasformazzjoni ta ’ maropitant fil- fwied.
Last Update: 2012-04-10
Usage Frequency: 4
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based on in vitro studies, empagliflozin does not inhibit, inactivate, or induce cyp450 isoforms.
mill-istudji in vitro, empagliflozin ma jimpedixxix, jinattivax, jew jinduċi isoformi ta' cyp450.
Last Update: 2017-04-26
Usage Frequency: 1
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cyp1a and cyp3a-related enzymes were identified as the feline isoforms involved in the hepatic biotransformation of maropitant.
cyp2d15 u cyp3a12 kienu identifikati bħala l-forom fil-qtates involuti fil- bijotrasformazzjoni ta’ maropitant fil-fwied.
Last Update: 2017-04-26
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it is unlikely that atosiban inhibits hepatic cytochrome p450 isoforms in humans (see section 4.5).
ma jidhirx li l- atosiban iwaqqaf l- effett ta ’ l- isoforomi ta ’ cytochrome p450 tal- fwied (ara sezzjoni 4. 5 prodotti mediċinali oħra li ma jaqblux ma ’ dan il- prodott u affarjiet oħra li jistgħu jibdlu l- effett farmaċewtiku tal- prodott).
Last Update: 2011-10-23
Usage Frequency: 1
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in vitro evaluation indicated that trifluridine and fty had no inductive effect on human cyp isoforms (see section 5.2).
evalwazzjoni in vitro indikat li trifluridine u fty ma kellhomx effett ta’ induzzjoni fuq l-iżoformi cyp tal-bnedmin (ara sezzjoni 5.2).
Last Update: 2017-04-26
Usage Frequency: 1
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vardenafil is metabolised predominantly by hepatic enzymes via cytochrome p450 (cyp) isoform 3a4, with some contribution from cyp3a5 and cyp2c isoforms.
vardenafil fil-biċċa l-kbira huwa mmetabolizzat mill-enzimi tal-fwied li jużaw ċitokromju p450 (cyp) isoform 3a4, bi ftit kontribuzzjoni mill-isoformi cyp3a5 u cyp2c.
Last Update: 2017-04-26
Usage Frequency: 1
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fentanyl is metabolised in the liver and in the intestinal mucosa to norfentanyl by cyp3a4 isoform.
fentanyl huwa metabolizzat fil-fwied u fil-mukuża tal-musrana għal norfentanyl permezz ta’ isoforma ta’ cyp3a4.
Last Update: 2017-04-26
Usage Frequency: 3
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