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malignant transformation begins in the skin or epithelium of the fistula and infiltrate the adjacent tissues, including bone.
a transformação maligna inicia-se na pele ou no epitélio da fístula e infiltra os tecidos adjacentes, incluindo o osso.
catheters can be a direct route of transmission for pathogenic microorganisms to migrate from the skin into the blood, and such organisms can directly infiltrate the thorax via a catheter.
os cateteres podem ser uma rota de transmissão direta de microrganismos da pele para o corpo, e tais organismos podem se infiltrar diretamente no tórax através de um cateter.
we postulate that the pathophysiology of acd to weak haptens is similar to that of acd to strong haptens and involves cd8 effectors able to infiltrate the skin in sensitized individuals.
postulamos que a fisiopatologia da dca a haptenos fracos é semelhante à da dca a haptenos fortes e envolve efetores cd8 capazes de infiltrar a pele em indivíduos sensibilizados.
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