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patients had opioid-induced constipation (< 3 rescue medication-free bowel movements per week during the screening period).
pacienti mali opioidov indukovanú zápchu (počas obdobia skríningu mali <3 stolice týždenne bez podania záchrannej liečby).
the study treatment period was 12 months preceded by a 4- to 9-week screening period during which vitamin d and elemental calcium supplements were taken for at least 2 weeks.
liečba v štúdii trvala 12 mesiacov a predchádzalo jej 4- až 9-týţdňové obdobie skríningu, v ktorom sa počas najmenej 2 týždňov užívali doplnky vitamínu d a elementárneho vápnika.