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elvitegravir does not inhibit human topoisomerases i or ii.
elvitegravir neinhibuje ľudské topoizomerázy i ani ii.
Last Update: 2017-04-26
Usage Frequency: 1
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in vitro resistance to moxifloxacin is acquired through a stepwise process by target site mutations in both type ii topoisomerases, dna gyrase and topoisomerase iv.
14 in vitro sa získava rezistencia na moxifloxacín prostredníctvom postupného procesu mutácií cieľového miesta na oboch topoizomerázach typu ii, dna gyráze a topoizomeráze iv.
Last Update: 2012-04-12
Usage Frequency: 4
Quality:
the bactericidal action of moxifloxacin results from the inhibition of both type ii topoisomerases (dna gyrase and topoisomerase iv) required for bacterial dna replication, transcription and repair.
baktericídny účinok moxifloxacínu vychádza z inhibície oboch topoizomeráz typu ii (dna gyrázy a topoizomerázy iv), ktoré sú potrebné na replikáciu, transkripciu a reparáciu bakteriálnej dna.
Last Update: 2012-04-12
Usage Frequency: 2
Quality:
235 as a fluoroquinolone antibacterial agent, the bactericidal action of ciprofloxacin results from the inhibition of both type ii topoisomerase (dna-gyrase) and topoisomerase iv, required for bacterial dna replication, transcription, repair and recombination.
231 baktericídny účinok ciprofloxacínu ako fluorochinolónového antibiotika vyplýva z inhibície oboch topoizomeráz typu ii (dna gyrázy) a topoizomerázy iv, ktoré sú potrebné na replikáciu, transkripciu, reparáciu a rekombináciu bakteriálnej dna.
Last Update: 2012-04-12
Usage Frequency: 5
Quality: