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the full thickness of the epithelium shows architectural disturbances such as irregular epithelial stratification, irregular polarity of basal cells, dropshaped rete ridges with cytological atypia of anisonucleosis, nuclear and cellular pleomorphism, and atypical mitotic figures.
el espesor completo del epitelio muestra alteraciones arquitectónicas tales como estratificación epitelial irregular, polaridad irregular de las células basales, puentes intercelulares con forma de gota y atipia citológica con anisonucleosis, pleomorfismo nuclear y celular y figuras mitóticas atípicas.