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stimulanttien samanaikainen käyttö oli sallittua kaikissa tutkimuksissa (paitsi tutkimuksen 2 aktiivihoitovaiheessa); masennuslääkkeiden käyttö lopetettiin ennen aktiivihoitoa kaikissa muissa tutkimuksissa paitsi tutkimuksessa 2.
the effectiveness of sodium oxybate for the treatment of narcolepsy symptoms was established in four multicentre, randomised, double-blind, placebo-controlled, parallel-group trials (trial 1, 2, 3 and 4) in patients with narcolepsy with cataplexy except for trial 2 where cataplexy was not required for enrolment concomitant stimulant use was permitted in all trials (except for the active-treatment phase of trial 2); antidepressants were withdrawn prior to active treatment in all trials with the exception of trial 2.
Last Update: 2011-10-23
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natriumoksibaatin tehokkuus narkolepsiaoireiden hoidossa on osoitettu neljässä satunnaistetussa kaksoissokkoutetussa lumelääkekontrolloidussa rinnakkaisryhmillä toteutetussa monikeskustutkimuksessa (tutkimukset 1, 2, 3 ja 4) narkolepsiapotilailla, joilla esiintyy katapleksiaa (ainoastaan tutkimuksessa 2 katapleksia ei ollut mukaanottokriteeri) .stimulanttien samanaikainen käyttö oli sallittua kaikissa tutkimuksissa (paitsi tutkimuksen 2 aktiivihoitovaiheessa); masennuslääkkeiden käyttö lopetettiin ennen aktiivihoitoa kaikissa muissa tutkimuksissa paitsi tutkimuksessa 2.
the effectiveness of sodium oxybate for the treatment of narcolepsy symptoms was established in four multicentre, randomised, double-blind, placebo-controlled, parallel-group trials (trial 1, 2, 3 and 4) in patients with narcolepsy with cataplexy except for trial 2 where cataplexy was not required for enrolment concomitant stimulant use was permitted in all trials (except for the active-treatment phase of trial 2); antidepressants were withdrawn prior to active treatment in all trials with the exception of trial 2.
Last Update: 2008-03-04
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