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vorikonatsoli vaikuttaa fungisidisesti aspergillus spp.:hen in vitro.
voriconazole has in vitro fungicidal activity against aspergillus spp.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
aspergillus-infektiot -tehokkuus huonon ennusteen aspergilloosi-potilailla vorikonatsoli vaikuttaa fungisidisesti aspergillus spp.: en in vitro.
successful outcome in this section is defined as complete or partial response.
Last Update: 2008-03-04
Usage Frequency: 1
Quality:
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isavukoatsolilla vaikuttaa fungisidisesti estämällä sienen solukalvon avainkomponentin ergosterolin synteesiä estämällä sytokromi p450 -riippuvaista entsyymiä lanosteroli-14-alfademetylaasia, joka vastaa lanosterolin muuttamisesta ergosteroliksi.
isavuconazole demonstrates a fungicidal effect by blocking the synthesis of ergosterol, a key component of the fungal cell membrane, through the inhibition of cytochrome p-450-dependent enzyme lanosterol 14-alpha-demethylase, responsible for the conversion of lanosterol to ergosterol.
Last Update: 2017-04-26
Usage Frequency: 1
Quality: