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kun infliksimabia annettiin viidellä annostasolla (1, 3, 5, 10 tai 20 mg/kg) laskimonsisäisinä kertainfuusioina, tuloksena oli lineaarinen, annoksen kokoon suhteutuva seerumin maksimikonsentraation (cmax) ja auc:n kasvu.
single intravenous infusions of 1, 3, 5, 10 or 20 mg/kg of infliximab yielded dose proportional increases in the maximum serum concentration (cmax) and area under the concentration-time curve (auc).
Last Update: 2017-04-26
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