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tutkimuksissa on vahvistettu tenofoviirin aktiivisen tubulaarisen erityksen reitin kulkevan proksimaaliseen tubulussoluun human organic anion transporters (hoat) 1 ja 3 kautta, ja erittyvän virtsaan monilääkeresistentin proteiinin mrp 4 (multidrug resistant protein 4) avulla.
estudos estabeleceram a via da secreção tubular activa do tenofovir a ser reabsorvido para as células tubulares proximais através dos transportadores humanos de aniões orgânicos (hoat) 1 e 3 e a secreção para a urina através da mrp 4 (mrp 4- multidrug resistant protein 4).
Last Update: 2011-10-23
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