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a tenofovir intracellulárisan tenofovir monofoszfáttá és az aktív komponenssé, tenofovir-difoszfáttá alakul át.
tenofovir is converted intracellularly to tenofovir monophosphate and to the active component, tenofovir diphosphate.
Last Update: 2017-04-26
Usage Frequency: 4
Quality:
a cidofovir endocitosis révén kerül a sejtbe, és cidofovir- monofoszfáttá, majd cidofovir- difoszfáttá foszforilálódik.
cidofovir enters cells by fluid-phase endocytosis and is phosphorylated to cidofovir monophosphate and subsequently to cidofovir diphosphate.
Last Update: 2012-04-12
Usage Frequency: 3
Quality:
a cidofovir folyékony fázisú endocitosis révén kerül a sejtbe, és cidofovir-monofoszfáttá, majd cidofovir-difoszfáttá foszforilálódik.
cidofovir enters cells by fluid-phase endocytosis and is phosphorylated to cidofovir monophosphate and subsequently to cidofovir diphosphate.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
az 5-fu a sejteken belül foszforilációval aktiválódik aktív metabolitjává, 5-fluoro-deoxiuridin-monofoszfáttá (fdump).
5-fu is activated within cells by phosphorylation to its active metabolite, 5-fluoro-deoxyuridine-monophosphate (fdump).
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
a nelarabint az adenozin-deamináz (ada) igen gyorsan ara-g-vé demetilezi, majd a deoxiguanozin-kináz és deoxicitidin-kináz intracellulárisan 5’-monofoszfáttá foszforilálja.
nelarabine is rapidly demethylated by adenosine deaminase (ada) to ara-g and then phosphorylated intracellularly by deoxyguanosine kinase and deoxycytidine kinase to its 5’-monophosphate metabolite.
Last Update: 2017-04-26
Usage Frequency: 5
Quality: