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evicel neirotoksicitātes pētījumos ar trušiem subdurāli ievadīta preparāta neirotoksiska ietekme uz dzīvniekiem netika konstatēta.
neurotoxicity studies performed with evicel confirmed that subdural administration in the rabbit was not associated with any evidence of neurotoxicity.
noteiktas takrolima kombinācijas ar vielām, kam piemīt nefrotoksiska vai neirotoksiska ietekme, var palielināt šās ietekmes risku (skatīt 4.5. apakšpunktu).
certain combinations of tacrolimus with substances known to have nephrotoxic or neurotoxic effects may increase the risk of these effects (see section 4.5).
attīstoties smagām perifērām neirotoksiskas dabas parādībām, nepieciešams samazināt preparāta devu (skatīt 4.2. apakšpunktu).
the development of severe peripheral neurotoxicity requires a reduction of dose (see section 4.2).