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tačiau šis padidėjimas atsirado labai viršijant didžiausią terapinę dozę, buvo grįžtamas, nebuvo susijęs su degeneraciniais mikroskopiniais kepenų arba antinksčių pokyčiais.
repeated oral administration of zaleplon to rats and dogs elicited increases in liver and adrenal weights; however, these increases occurred at high multiples of the maximum therapeutic dose, were reversible, were not associated with degenerative microscopic changes in liver or adrenal glands, and were consistent with effects in animals with other compounds that bind to benzodiazepine receptors.
Last Update: 2011-10-23
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-jeigu js kraujo giminaiciai sirgo degeneracine aki liga (pvz., pigmentiniu retinitu);
-if your family has a history of degenerative eye diseases (such as retinitis pigmentosa)
Last Update: 2008-03-04
Usage Frequency: 6
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