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dėl to neskatinamas bradikinino medijuojamas nepageidaujamas poveikis.
consequently, there is thus no increase in bradykinin-mediated undesirable effects.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
pagrindinis metabolizmo bdas yra n-demetilinimas, daugiausia medijuojamas cyp3a.
the main metabolic pathway, n-demethylation, is mediated mainly by cyp 3a.
Last Update: 2008-03-04
Usage Frequency: 1
Quality:
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pagrindinis metabolizmo būdas yra n-demetilinimas, daugiausia medijuojamas cyp3a.
the main metabolic pathway, n-demethylation, is mediated mainly by cyp3a.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
Šis poveikis medijuojamas endotelinui jungiantis su eta ir etb receptoriais, esančiais endotelyje ir kraujagyslių lygiųjų raumenų ląstelėse.
these effects are mediated by endothelin binding to eta and etb receptors located in the endothelium and vascular smooth muscle cells.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
rūkančiųjų cinakalceto koncentracija plazmoje gali būti mažesnė dėl cyp1a2 medijuojamo metabolizmo indukcijos.
plasma levels of cinacalcet may be lower in smokers due to induction of cyp1a2-mediated metabolism.
Last Update: 2017-04-26
Usage Frequency: 7
Quality: