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adenokarċinomi fl-utru, ta’ oriġini epiġenetika, jistgħu jkunu marbuta ma’ induzzjoni ta’ enżima tal-familja cyp1.
uterine adenocarcinomas, of epigenetic origin, could be related to an enzyme induction of cyp1 family.
Last Update: 2017-04-26
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fi studju li sar fuq il-ġrieden dwar il- karċinoġeniċita`, li dam sejjer ta’ 21 xahar, kien hemm żieda fl-inċidenza ta’ tumuri taċ-ċelluli interstizjali tat-testikoli, adenomi tal-prostata u adenokarċinomi fl-annimali ta’ sess maskil, meta ngħataw 41 jew 210 mg/kg,, u l-lejomajoblastoma tal-prostata fl-annimali ta’ sess maskil li ngħataw 210 mg/kg.
in a 21-month carcinogenicity study in mice, there was an increased incidence of testicular interstitial cell tumours and prostatic adenomas and adenocarcinomas in males given 41 or 210 mg/kg, and prostatic leiomyoblastoma in males given 210 mg/kg.
Last Update: 2017-04-26
Usage Frequency: 3
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