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o metabolito mono-desmetilado é farmacologicamente ativo.
the mono-demethylated metabolite is pharmacologically active.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
foram obtidos resultados semelhantes em relação ao metabolito mono- desmetilado ativo.
similar results were obtained for the active mono-demethylated metabolite.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
o pimobendan é desmetilado oxidativamente no seu maior metabolito, o-desmetil pimobendan.
pimobendan is oxidatively demethylated to its major active metabolite, o-desmethyl pimobendan.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
o outro metabolito, o glucuronido conjugado do cimicoxib desmetilado, é eliminado na urina.
the other metabolite, glucuronide conjugate of the demethylated cimicoxib, is eliminated in urine.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
a ligação do metabolito n-desmetilado às proteínas plasmáticas é semelhante à do composto inicial.
the plasma protein binding of the n-demethylated metabolite is similar to that of the parent compound.
Last Update: 2017-04-26
Usage Frequency: 7
Quality:
o principal metabolito em circulação resulta da n- desmetilação do sildenafil.
the major circulating metabolite results from n-demethylation of sildenafil.
Last Update: 2017-04-26
Usage Frequency: 7
Quality: