Results for transpeptidação translation from Portuguese to English

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transpeptidação

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Portuguese

atua primariamente pela inibição de um passo na síntese da parede celular bacteriana transpeptidação, que resulta na lise celular bacteriana espontânea.

English

it primarily acts by inhibiting one step in the synthesis of the bacterial cell wall transpeptidation, which results in spontaneous bacterial cell lysis.

Last Update: 2020-08-02
Usage Frequency: 1
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Reference: Luizfernando4

Portuguese

após um antibiótico beta-lactâmico se ter ligado a estes receptores, a reacção de transpeptidação é inibida e a síntese de peptidoglicanos é bloqueada.

English

after a -lactam antibiotic has bound to these receptors, the transpeptidation reaction is inhibited and peptidoglycan synthesis is blocked.

Last Update: 2008-03-04
Usage Frequency: 2
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Reference: Luizfernando4
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Portuguese

a oritavancina tem três mecanismos de ação: (i) inibição da etapa de transglicosilação (polimerização) da biossíntese da parede celular através da ligação ao péptido de origem dos precursores do peptidoglicano, (ii) inibição da etapa de transpeptidação (ligação cruzada) da biossíntese da parede celular através da ligação aos segmentos de ponte dos péptidos da parede celular, e (iii) disrupção da integridade da membrana bacteriana causando a despolarização, permeabilização e morte rápida da célula.

English

oritavancin has three mechanisms of action: (i) inhibition of the transglycosylation (polymerization) step of cell wall biosynthesis by binding to the stem peptide of peptidoglycan precursors; (ii) inhibition of the transpeptidation (crosslinking) step of cell wall biosynthesis by binding to the peptide bridging segments of the cell wall; and (iii) disruption of bacterial membrane integrity, leading to depolarization, permeabilization, and rapid cell death.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

Reference: Luizfernando4

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