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não há acumulação de rivastigmina ou do metabolito descarbamilado em doentes com doença de alzheimer.
rivastigmin eller den dekarbamylerade metaboliten ackumuleras ej hos patienter med alzheimers sjukdom.
Last Update: 2012-04-10
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10 metabolismo a rivastigmina é rápida e extensivamente metabolizada (semi- vida plasmática de aproximadamente 1 hora), primariamente via hidrólise mediada pela colinesterase, no metabolito descarbamilado.
metabolism rivastigmin metaboliseras snabbt och i stor utsträckning (halveringstid i plasma cirka 1 timme), via kolinesteras- medierad hydrolys till den dekarbamylerade metaboliten.
Last Update: 2012-04-10
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