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activarea constitutivă a receptorilor fcdp sau a abl protein-tirozin kinazelor ca o consecinţă a fuzionării cu diverse proteine asociate sau producerea constitutivă a fcdp au fost implicate în patogeneza mds/mpd, she/lec şi pdfs.
constitutive activation of the pdgf receptor or the abl protein tyrosine kinases as a consequence of fusion to diverse partner proteins or constitutive production of pdgf have been implicated in the pathogenesis of mds/mpd, hes/cel and dfsp.
Last Update: 2017-04-26
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