Results for demetilvenlafaxina translation from Romanian to English

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demetilvenlafaxina

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venlafaxina şi metabolitul său activ, o- demetilvenlafaxina sunt excretate în laptele matern uman.

English

venlafaxine and its active metabolite, o-desmethylvenlafaxine, are excreted in breast milk.

Last Update: 2012-04-11
Usage Frequency: 4
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Romanian

metoprololul nu a afectat parametrii farmacocinetici ai venlafaxinei şi ai metabolitului său activ, o- demetilvenlafaxina.

English

metoprolol did not alter the pharmacokinetic profile of venlafaxine or its active metabolite, o-desmethylvenlafaxine.

Last Update: 2012-04-11
Usage Frequency: 2
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Romanian

venlafaxina este metabolizată în proporţie mare, în principal la metabolitul său activ, o- demetilvenlafaxina (odv).

English

venlafaxine is extensively metabolised, primarily to the active metabolite, o-desmethylvenlafaxine (odv).

Last Update: 2012-04-11
Usage Frequency: 2
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Romanian

studiile in vitro şi in vivo indică faptul că venlafaxina este metabolizată de către cyp3a4 la un metabolit minor, mai puţin activ, n- demetilvenlafaxina.

English

in vitro and in vivo studies indicate that venlafaxine is metabolised to a minor, less active metabolite, n-desmethylvenlafaxine, by cyp3a4.

Last Update: 2012-04-11
Usage Frequency: 2
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Romanian

studiile preclinice au arătat că venlafaxina şi metabolitul său major, o- demetilvenlafaxina (odv), sunt inhibitori ai recaptării serotoninei şi noradrenalinei.

English

preclinical studies have shown that venlafaxine and its major metabolite, o-desmethylvenlafaxine (odv), are inhibitors of serotonin and noradrenaline reuptake.

Last Update: 2012-04-11
Usage Frequency: 2
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Romanian

ketoconazol (inhibitor al cyp3a4) un studiu farmacocinetic cu ketoconazol la pacienţi metabolizatori rapizi (mr) sau lenţi (ml) pe calea cyp2d6 a indicat o valoare mai mare a asc pentru venlafaxină (70% şi 21% la pacienţii cyp2d6 ml, respectiv, mr) şi o- demetilvenlafaxină (33% şi 23% la pacienţii cyp2d6 ml, respectiv, mr) în urma administrării de ketoconazol.

English

ketoconazole (cyp3a4 inhibitor) a pharmacokinetic study with ketoconazole in cyp2d6 extensive (em) and poor metabolisers (pm) resulted in higher auc of venlafaxine (70% and 21% in cyp2d6 pm and em subjects, respectively) and o-desmethylvenlafaxine (33% and 23% in cyp2d6 pm and em subjects, respectively) following administration of ketoconazole.

Last Update: 2012-04-11
Usage Frequency: 2
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