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glykopyróniumbromid je antagonista muskarínových receptorov s vysokou afinitou.
glycopyrronium bromide is a high affinity muscarinic receptor antagonist.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
farbivá s afinitou vlákien (rozpustné alebo nerozpustné)
colour matter with fibre affinity (soluble or insoluble).
Last Update: 2014-11-21
Usage Frequency: 1
Quality:
látky s vysokou afinitou voči povrchu inkubačných systémov).
substances with a high affinity to the surface of incubation systems).
Last Update: 2014-11-21
Usage Frequency: 2
Quality:
viaže sa s vysokou afinitou na izoformy vegf-a (napr.
it binds with high affinity to the vegf-a isoforms (e.g.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
toto zistenie je v súlade s nízkou afinitou tadalafilu k pde6 v porovnaní s pde5.
this finding is consistent with the low affinity of tadalafil for pde6 compared to pde5.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
trieda i štiepi nerozpustnú trojitú závitnicu kolagénu s vyššou afinitou ako kolagenáza triedy ii.
class i cleaves insoluble triple helical collagen with higher affinity than class ii collagenase.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
je to trojdonorový ligand, ktorý viaže železo s vysokou afinitou v pomere 2:1.
it is a tridentate ligand that binds iron with high affinity in a 2:1 ratio.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
preto u liekov s vysokou afinitou k dopamínovému nosičovi môže dôjsť k interferencii pri používaní diagnostiky datscanom.
medicines that bind to the dopamine transporter with high affinity may therefore interfere with datscan diagnosis.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
macitentan sa vyznačuje vysokou afinitou a dlhodobou väzbou na et receptory v ľudských bunkách hladkých svalov pľúcnych artérií.
macitentan displays high affinity and sustained occupancy of the et receptors in human pulmonary arterial smooth muscle cells.
Last Update: 2017-04-26
Usage Frequency: 1
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bezpečnosť omalizumabu sa sledovala u makaka krabožravého, pretože omalizumab sa viaže na ige s podobnou afinitou u makaka a u ľudí.
the safety of omalizumab has been studied in the cynomolgus monkey, since omalizumab binds to cynomolgus and human ige with similar affinity.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
biologické ú inky raloxifénu, rovnako ako estrogénov, sú sprostredkované vysokou afinitou väzby na estrogénové receptory a reguláciou génovej expresie.
raloxifene 'biological actions, like those of oestrogen, are mediated through high affinity binding to s oestrogen receptors and regulation of gene expression.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
Warning: This alignment may be wrong.
Please delete it you feel so.
telmisartan vytesňuje angiotenzín ii s veľmi vysokou afinitou z jeho väzbového miesta na subtype receptora at1 , ktorý je zodpovedný za známe pôsobenie angiotenzínu ii.
telmisartan displaces angiotensin ii with very high affinity from its binding site at the at1 receptor subtype, which is responsible for the known actions of angiotensin ii.
Last Update: 2017-04-26
Usage Frequency: 4
Quality:
cetuximab sa viaže na egfr s afinitou, ktorá je približne 5- až 10-násobne vyššia než afinita endogénnych ligandov.
cetuximab binds to the egfr with an affinity that is approximately 5- to 10-fold higher than that of endogenous ligands.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
blokuje tiež α2c-adrenergické receptory a α2a-adrenergické receptory s väzbovou afinitou 10,8, respektíve 40,7 nm.
it also blocks α2c-adrenergic receptors and α2a-adrenergic receptors with a binding affinity of 10.8 and 40.7 nm respectively.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
bosentan je duálny antagonista receptora pre endotelín (era) s afinitou pre endotelínový receptor a a b (eta a etb).
bosentan is a dual endothelin receptor antagonist (era) with affinity for both endothelin a and b (eta and etb) receptors.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
navyše štúdie klinických interakcií s nelfinavirom, stredne silným inhibítorom oatp, a pravastatínom, inhibítorom oatp s malou afinitou, neviedli ku klinicky významným zmenám plazmatických hladín sitaxentanu.
moreover, clinical interaction studies with nelfinavir, a moderately potent oatp inhibitor, and pravastatin, a low affinity oatp inhibitor, did not result in clinically significant changes in sitaxentan plasma levels.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
joflupán sa tiež viaže na serotonínový nosič na 5-ht neurónoch, avšak s nižšou väzbovou afinitou (približne10- násobne).
ioflupane also binds to the serotonin transporter on 5-ht neurons but with lower (approximately 10-fold) binding affinity.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
ritonavir sa viaže s porovnateľnou afinitou na ľudský alfa 1- kyslý glykoproteín (aag) a na ľudský sérový albumín (hsa).
ritonavir binds to both human alpha 1-acid glycoprotein (aag) and human serum albumin (hsa) with comparable affinities.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
in vitro afinita rekombinantného hlh na lh/cg receptor na bunkách tumoru leydigových buniek (ma-10) je medzi afinitou hcg a afinitou hypofyzárneho hlh, avšak rádovo je rovnaká.
in vitro the affinity binding of recombinant hlh to the lh/cg receptor on leydig tumour cells (ma-10) is between that for hcg and that of pituitary hlh, but within the same order of magnitude.
Last Update: 2017-04-26
Usage Frequency: 3
Quality: