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sukcinylacetón inhibuje syntézu porfyrínu a to vedie k akumulácii 5-aminolevulinátu.
succinylacetone inhibits the porphyrin synthesis pathway leading to the accumulation of 5-aminolevulinate.
Last Update: 2017-04-26
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počas zahájenia liečby alebo pri zhoršení stavu je nevyhnutné podrobnejšie sledovať všetky dostupné biochemické parametre (napr. plazmatické hladiny sukcinylacetónu, hladinu 5- aminolevulinátu (ala) v moči a aktivitu erytrocytárnej porfobilinogén (pbg) - syntázy).
however, in addition to the tests above, during the initiation of therapy or if there is a deterioration it may be necessary to follow more closely all available biochemical parameters (i. e. plasma succinylacetone, urine 5-aminolevulinate (ala) and erythrocyte porphobilinogen (pbg)-synthase activity).
Last Update: 2012-04-12
Usage Frequency: 4
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