Results for norfentanil translation from Slovenian to English

glavni presnovek, norfentanil, je neaktiven.
the major metabolite, norfentanyl is inactive.

norfentanil v študijah na živalih ni farmakološko aktiven.
norfentanyl is not pharmacologically active in animal studies.

fentanil presnavlja izooblika citokroma cyp3a4 v jetrih v norfentanil.
fentanyl is metabolised in the liver to norfentanyl by cytochrome cyp3a4 isoform.

fentanil se presnavlja zlasti v jetrih v norfentanil ob pomoči izoforme cyp3a4.
fentanyl is metabolised primarily in the liver to norfentanyl by cyp3a4 isoform.

fentanil se presnavlja v jetrih in v črevesni sluznici v norfentanil s pomočjo izoforme cyp3a4.
fentanyl is metabolised in the liver and in the intestinal mucosa to norfentanyl by cyp3a4 isoform.

fentanil se metabolizira primarno s cyp3a4 v številne farmakološko neaktivne metabolite, med njimi v norfentanil.
fentanyl is metabolised primarily via cyp3a4 to a number of pharmacologically inactive metabolites, including norfentanyl.

objavljena literatura navaja, da polimorfizma z enojnim nukleotidom cyp3a4*22 in cyp3a5*3 vplivata na presnovo fentanila v norfentanil s potencialom za povečano izpostavljenost fentanilu pri bolnikih s temi genetskimi polimorfizmi.
published literature has indicated that the cyp3a4*22 and cyp3a5*3 single nucleotide polymorphisms influence fentanyl to norfentanyl metabolism with the potential for increased fentanyl exposure in patients with these genetic polymorphs.