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reverzni prelom
reverse fault
Last Update: 2014-11-18
Usage Frequency: 1
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metoda: hplc na reverzni fazi
method: reversed-phase hplc
Last Update: 2014-11-21
Usage Frequency: 3
Quality:
reagenti za hplc na reverzni fazi.
reagents for reversed phase hplc.
Last Update: 2014-11-21
Usage Frequency: 3
Quality:
metoda hplc na reverzni fazi to možnost izključuje.
the reversed-phase hplc method excludes this possibility.
Last Update: 2014-11-21
Usage Frequency: 3
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njun glavni način učinkovanja je prekinitev verige pri virusni reverzni transkripciji.
their main modes of action are as chain terminators of viral reverse transcription.
Last Update: 2017-04-26
Usage Frequency: 3
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njegov glavni način delovanja je prekinitev verige pri virusni reverzni transkripciji.
its main mode of action is as a chain terminator of viral reverse transcription.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
Če je rezultat pozitiven, je treba uporabiti hplc-kromatografijo na reverzni fazi.
if the result is positive, the reversed-phase hplc procedure described below must be applied.
Last Update: 2014-11-21
Usage Frequency: 3
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za sedaj ni dokazov da bi dnevni odmerek 10 mg dipivoksiladefovirata povzročil nastanek mutacije za rezistenco povezane z adefovirjem v hiv reverzni transkriptazi.
to date there is no evidence that daily dosing with 10 mg adefovir dipivoxil results in emergence of adefovir-associated resistance mutations in the hiv reverse transcriptase.
Last Update: 2017-04-26
Usage Frequency: 1
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podobno je majhna možnost navzkrižne odpornosti med nevirapinom in nukleozidnimi zaviralci reverzne transkriptaze, ker imajo molekule različna vezavna mesta na reverzni transkriptazi.
similarly the potential for cross-resistance between nevirapine and nrtis is low because the molecules have different binding sites on the reverse transcriptase.
Last Update: 2017-04-26
Usage Frequency: 1
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amesov reverzni mutacijski test je bil za atazanavir negativen, toda in vitro so odkrili pojav kromosomskih aberacij, in sicer tako s presnovno aktivacijo kot brez nje.
atazanavir was negative in an ames reverse-mutation assay but did induce chromosomal aberrations in vitro in both the absence and presence of metabolic activation.
Last Update: 2017-04-26
Usage Frequency: 2
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odpornost na celičnih kulturah: v primerjavi z divjim tipom hbv so lvdr virusi z rtm204v in rtl180m substitucijami v reverzni transkriptazi 8-krat manj občutljivi za entekavir.
resistance in cell culture: relative to wild-type hbv, lvdr viruses containing rtm204v and rtl180m substitutions within the reverse transcriptase exhibit 8-fold decreased susceptibility to entecavir.
Last Update: 2017-04-26
Usage Frequency: 3
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poleg tega je bila s tenofovirjem izbrana substitucija k70e pri reverzni transkriptazi hiv-1, kar je povzročilo nizko raven zmanjšane občutljivosti za abakavir, emtricitabin, tenofovir in lamivudin.
in addition, a k70e substitution in hiv-1 reverse transcriptase has been selected by tenofovir and results in low-level reduced susceptibility to abacavir, emtricitabine, tenofovir and lamivudine.
Last Update: 2017-04-26
Usage Frequency: 1
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določitev ps in pe kot derivatov o-ftaldialdehida (opa) s hplc na reverzni fazi (rp) in fluorescenčno detekcijo.
determination of ps and pe as o-phthaldialdehyde (opa) derivatives by reversed-phase (rp) hplc and fluorescence detection.
Last Update: 2014-11-17
Usage Frequency: 1
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l10f, i13v, v32i, l33f, m36i, k45i, i54v/ t, a71v, v82l, i84v ter mutacijo na mestu cepitve gag poliproteina ca/ p2 reverzni genski preizkusi so pokazali, da je moralo biti za razvoj več kot 10- kratne odpornosti proti tipranavirju prisotnih 6 mutacij v proteazi (i13v, v32i, l33f, k45i, v82l, i84v), medtem ko je bila pri genotipu s polnimi 10 mutacijami odpornost proti tipranavirju 69- kratna.
reverse genetic experiments showed that the presence of 6 mutations in the protease (i13v, v32i, l33f, k45i, v82l, i84v) was required to confer > 10-fold resistance to tipranavir while the full 10-mutation genotype conferred 69-fold resistance to tipranavir.
Last Update: 2011-10-23
Usage Frequency: 1
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