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el crossing-over se determina generalmente por la producción de colonias o sectores recesivos homocigotos a partir de una cepa heterocigota, mientras que la conversión génica lo es mediante la producción de inversores prototróficos en una cepa auxotrofa heteroalélica portadora de dos alelos defectuosos distintos del mismo gen.
crossing-over is generally assayed by the production of recessive homozygous colonies or sectors produced in a heterozygous strain, whereas gene conversion is assayed by the production of prototrophic revertants produced in an auxotrophic heteroallelic strain carrying two different defective alleles of the same gene.