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Spanish

lipofilia de los AINE

English

lipophilicity of nonsteroidal anti-inflammatory drugs

Last Update: 2014-11-04
Subject: Social Science
Usage Frequency: 4
Quality:

Reference:

Spanish

Se desconoce si memantina se excreta por la leche materna pero, teniendo en cuenta la lipofilia del principio activo, es probable que así sea.

English

It is not known whether memantine is excreted in human breast milk but, taking into consideration the lipophilicity of the substance, this probably occurs.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 9
Quality:

Reference:

Spanish

Esto puede deberse a la lipofilia del fenilbutirato de sodio y a las consiguientes diferencias en el volumen de distribución.

English

This may be due to the lipophilicity of sodium phenylbutyrate and consequent differences in volume of distribution.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 3
Quality:

Reference:

Spanish

Debido a sus características de lipofilia, la doxiciclina se distribuye con facilidad a los tejidos de los animales, presentando volúmenes de distribución de 0,53 l/ kg.

English

Provided its lipophilic properties doxycycline is easily distributed in animal tissues, showing volumes of distribution of 0.53 l/ kg.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:

Reference:

Spanish

Parece que el riesgo de aparición de miopatía asociado al tratamiento con estatinas es dependiente de la exposición y, por tanto, puede variar con cada fármaco (debido a diferencias en la lipofilia y la farmacocinética), incluyendo su posología y su capacidad para tener interacciones medicamentosas.

English

The risk of myopathy with statins appears to be exposure-dependent and therefore may vary with individual drugs (due to lipophilicity and pharmacokinetic differences), including their dosage and potential for drug interactions.

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 1
Quality:

Reference:

Spanish

Así pues, para reducir esta fuente de variabilidad en los resultados de los ensayos relativos a las sustancias con fuerte lipofilia (es decir, con log Pow > 3), la bioconcentración debe expresarse en función del contenido lipídico, además del peso corporal total.

English

Thus, to reduce this source of variability in test results for those substances with high lipophilicity (i.e. with log Pow > 3), bioconcentration should be expressed in relation to lipid content in addition to whole body weight.

Last Update: 2016-05-28
Subject: Social Science
Usage Frequency: 1
Quality:

Reference:
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Spanish

Como hay una clara relación entre el potencial de bioconcentración y la lipofilia de numerosas sustancias orgánicas, también hay una relación correspondiente entre el contenido en lípidos de los peces del ensayo y las bioconcentraciones observadas de estas sustancias.

English

Since, for many organic substances, there is a clear relationship between the potential for bioconcentration and lipophilicity, there is also a corresponding relationship between the lipid content of the test fish and the observed bioconcentration of such substances.

Last Update: 2016-05-28
Subject: Social Science
Usage Frequency: 1
Quality:

Reference:

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