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en sänkning i den antiretrovirala aktiviteten av ritonavir är primärt associerad med proteasmutationerna v82a/f/t/s och i84v.
reduction in the antiretroviral activity of ritonavir is primarily associated with the protease mutations v82a/f/t/s and i84v.
Last Update: 2017-04-26
Usage Frequency: 5
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i pediatriska studierna apv20003 och apv29005 behandlades 67 pi-erfarna patienter med fosamprenavir/ritonavir och av de 22 genotypade isolaten som uppvisat virologisk svikt fann man nio patienter med proteasmutationer som uppkommit av behandlingen.
in the paediatric studies apv20003 and apv29005, 67 pi-experienced patients were treated with fosamprenavir / ritonavir and of 22 virological failure isolates genotyped, nine patients were found with treatment-emergent protease mutations.
Last Update: 2017-04-26
Usage Frequency: 5
Quality: