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onun yönetimi altında, dünyanın ilk çalışmaları radyoaktif izotoplar kullanılarak, neoplazmaların tedavisi içine yapılmıştır.
under her direction, the world's first studies were conducted into the treatment of neoplasms, using radioactive isotopes.
Last Update: 2016-03-03
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565555555222523333gİrİŞ kronik miyelomonositik lösemiler (cmml), miyelodisplastik ve miyeloproliferatif özelliklere sahip nadir miyeloid neoplazmalardır.1 wbc sayısı ile tanımlanan cmml'nin (mp cmml) miyeloproliferatif alt kümesi $ 13 3 109 /l,2,3 cmml'li hastaların % 40 50 'sini temsil eder ve kötü prognoza sahiptir.4 allojenik transplantasyon (hsct) için uygun olmayan mp cmml9astalarında, sitoredüksiyon
standard of care. in a previous randomized clinical trial, hydroxyurea (hy) provided superior response rates and survival versus oral etoposide in mpcmml with protocol-defined criteria for advanced disease, including blast excess, abnormal karyotype, significant cytopenias, or splenomegaly.5 response criteria in this trial accounted for improvement of both myelodysplastic and myeloproliferative traits of cmml, predating the more recent international myelodysplastic syndrome/myeloproliferative neoplasm response criteria.
Last Update: 2023-12-28
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