AGP 3.0-tilstand

AGP 3.0 mode

1, 5 - til 2 - fold, svarende til en 1, 5- gangs stigning af plasma AGP som imatinib binder stærkt til.
http://www.emea.europa.eu/

The increase is approximately 1.5- to 2-fold, corresponding to a 1.5-fold elevation of plasma AGP, to which imatinib binds strongly.
http://www.emea.europa.eu/

7 (AGP) , et imatinib-bindende protein, hos disse patienter.Der bør anvendes mindste startdosis til patienter med nedsat nyrefunktion.

In patients with impaired renal function, imatinib plasma exposure seems to be higher than that in patients with normal renal function, probably due to an elevated plasma level of alpha-acid glycoprotein (AGP) , an imatinib-binding protein, in these patients.Patients with renal impairment should be given the minimum starting dose.

Eksponeringen er ca.1, 5 -til 2 -fold, svarende til en 1, 5-gangs stigning af plasma AGP som imatinib binder stærkt til.

The increase is approximately 1.5-to 2-fold, corresponding to a 1.5-fold elevation of plasma AGP, to which imatinib binds strongly.

Plasmaeksponeringen synes at være højere hos patienter med nedsat nyrefunktion end hos patienter med normal nyrefunktion, formentlig på grund af forhøjede plasmaniveauer af alpha-acid glucoprotein (AGP) , et imatinib-bindende protein, hos disse patienter.

In patients with impaired renal function, imatinib plasma exposure seems to be higher than that in patients with normal renal function, probably due to an elevated plasma level of alpha-acid glycoprotein (AGP) , an imatinib-binding protein, in these patients.

55 i Glivec-behandling.Plasmaeksponeringen synes at være højere hos patienter med nedsat nyrefunktion end hos patienter med normal nyrefunktion, formentlig på grund af forhøjede plasmaniveauer af alpha-acid glucoprotein (AGP) , et imatinib-bindende protein, hos disse patienter.

In patients with impaired renal function, imatinib plasma exposure seems to be higher than that in patients with normal renal function, probably due to an elevated plasma level of alpha-acid glycoprotein (AGP) , an imatinib-binding protein, in these patients.

Maksimalt antal af AGP-kommandoer

Maximum number of AGP command