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tacrolimus er et immunosuppressivum af macrolid- typen, der farmakologisk tilhører klassen af calcineurin- hæmmere.
tacrolimus is a macrolide immunosuppressant belonging to the pharmacological class of the calcineurin inhibitors.
Last Update: 2012-04-12
Usage Frequency: 3
Quality:
i publicerede prospektive studier var tacrolimus primært immunosuppressivum i omkring 175 lungetransplanterede patienter, 475 pancreastransplanterede patienter og 630 intestinaltransplanterede patienter.
in prospective published studies tacrolimus was investigated as primary immunosuppressant in approximately 175 patients following lung, 475 patients following pancreas and 630 patients following intestinal transplantation.
Last Update: 2012-04-12
Usage Frequency: 4
Quality:
38 resultater fra publicerede data fra anden primær organtransplantation er blevet en accepteret behandling som primært immunosuppressivum i forbindelse med pancreas, lunge og intestinale transplantationer.
results from published data in other primary organ transplantation has evolved into an accepted treatment as primary immunosuppressive medicinal product following pancreas, lung and intestinal transplantation.
Last Update: 2012-04-12
Usage Frequency: 6
Quality:
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adækvat behandling med glukokortikoid og/ eller et andet immunosuppressivum ikke har responderet tilfredsstillende, eller som er intolerante over for eller har medicinske kontraindikationer mod sådanne behandlinger.
trudexa is indicated for treatment of severe, active crohn’ s disease, in patients who have not responded despite a full and adequate course of therapy with a corticosteroid and/ or an immunosuppressant; or who are intolerant to or have medical contraindications for such therapies.
Last Update: 2012-04-12
Usage Frequency: 4
Quality:
da tacrolimus er et effektivt immunosuppressivum, der virker ved at undertrykke t- lymfocytterne i huden, kan det efter chmps opfattelse ikke udelukkes, at tacrolimus påvirker udviklingen eller progressionen af en række forskellige hudforandringer.
as tacrolimus is an effective immunosuppressant that acts by suppressing t lymphocytes in the skin, the chmp was of the opinion that an effect of tacrolimus on the development or progression of a variety of skin lesions could not be excluded.
Last Update: 2012-04-12
Usage Frequency: 4
Quality:
humira er indiceret til behandling af svær, aktiv crohns sygdom hos patienter, som på trods af en adækvat behandling med glukokortikoid og/ eller et andet immunosuppressivum ikke har responderet tilfredsstillende, eller som er intolerante over for eller har medicinske kontraindikationer mod sådanne behandlinger.
humira is indicated for treatment of severe, active crohn’ s disease, in patients who have not responded despite a full and adequate course of therapy with a corticosteroid and/ or an immunosuppressant; or who are intolerant to or have medical contraindications for such therapies.
Last Update: 2012-04-11
Usage Frequency: 5
Quality: