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bortset fra andre omsætningsveje metaboliseres disse produkter yderligere via glucuronidering.
apart from other pathways these products are further metabolized via glucuronidation.
Last Update: 2012-04-12
Usage Frequency: 6
Quality:
et interaktionsstudie udført hos patienter, som var i behandling med ketokonazol og docetaxel, viste, at clearance af docetaxel blev reduceret til halvdelen på grund af ketokonazol, sandsynligvis fordi metabolismen af docetaxel involverer cyp3a4 som den største (eneste) metaboliske omsætningsvej.
a drug interaction study performed in patients receiving ketoconazole and docetaxel showed that the clearance of docetaxel was reduced by half by ketoconazole, probably because the metabolism of docetaxel involves cyp3a4 as a major (single) metabolic pathway.
Last Update: 2017-04-26
Usage Frequency: 4
Quality: