Results for vævskoncentrationerne translation from Danish to English

alligevel forventes det, at p-gp-hæmmere øger vævskoncentrationerne mere end plasmakoncentrationerne.
yet, p-gp inhibitors are expected to increase tissue concentrations more than plasma concentrations.

indehaverne af markedsføringstilladelse fremlagde ingen relevante oplysninger, der kunne give en sammenligning af vævskoncentrationerne efter peroral behandling med norfloxacin, ciprofloxacin, ofloxacin og levofloxacin.
the mahs did not provide any relevant information showing comparison of tissue concentrations after oral treatment with norfloxacin, ciprofloxacin, ofloxacin and levofloxacin.

samtidig administration af aliskiren 300 mg og ketoconazol 200 mg resulterede i en 76 % stigning i aliskirens auc, men p-gp-hæmmere som ketoconazol kan forventes at øge vævskoncentrationerne mere end plasmakoncentrationerne.
co-administration of aliskiren 300 mg with ketoconazole 200 mg resulted in a 76% increase in aliskiren auc but p-gp inhibitors such as ketoconazole are expected to increase tissue concentrations more than plasma concentrations.

i in vivo- undersøgelser hos rotter inducerede atazanavir ikke mikronukleus i knoglemarv, dna- beskadigelse i duodenum (comet assay) eller uplanlagt dna- reparation i leveren ved plasma - og vævskoncentrationer, der overskrider dem, der var klastogene in vitro.
in in vivo studies in rats, atazanavir did not induce micronuclei in bone marrow, dna damage in duodenum (comet assay), or unscheduled dna repair in liver at plasma and tissue concentrations exceeding those that were clastogenic in vitro.