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the immunoregulatory activities of granulocyte colony stimulating factor concerns notably cells of the neutrophilic granulocyte lineage which bear cell surface receptors for the protein.
de immunregulerende aktiviteter hos granulocyt-kolonistimulerende faktor vedrører navnligt celler fra den neutrofile granulocyt cellelinje, som bærer celleoverfladereceptorer til proteinet.
mixed cell/neutrophilic inflammation of the extra-hepatic ducts extended to the pancreas and/or duodenum at higher doses.
blandet celle-/neutrofilinflammation i de ekstrahepatiske galdegange bredte sig til pankreas og/eller duodenum ved højere doser.
in clinical trials, immune-related colitis was associated with evidence of mucosal inflammation, with or without ulcerations, and lymphocytic and neutrophilic infiltration.
i kliniske forsøg blev immunrelateret colitis associeret med tegn på slimhindeinflammation, med eller uden ulceration, samt infiltration af lymfocytter og neutrofile granulocytter.
in a study in rats, diffuse corneal edema with neutrophilic cell infiltration, and hyperplastic changes in the lenticular epithelium suggestive of a mild phototoxic reaction were observed in animals treated with 5 and 10 mg/kg ponatinib
i et studie med rotter blev der observeret diffus corneaødem med neutrofilcelleinfiltration og hyperplastiske forandringer i linseepitelet, hvilket tyder på en mild fototoksisk reaktion hos dyr, behandlet med 5 og 10 mg/kg ponatinib
neutrophilic dermatosis, photosensitivity, pigmentation disorder, panniculitis, skin ulcer, bullous conditions, nail disorder, palmar-plantar erythrodysesthesia syndrome, hair disorder
neutrofil dermatosis, fotosensitivitet, pigmenteringsforstyrrelse, panniculitis, hudsår, bulløse tilstande, neglelidelser, palmoplantar erytrodysæstesisyndrom, hårlidelser
skin and subcutaneous tissue disorders common: alopecia, acne, dry skin, urticaria, hyperhidrosis uncommon: dermatitis (including eczema) , acute febrile neutrophilic dermatosis, photosensitivity, pigmentation disorder, panniculitis, skin ulcer, bullous conditions, nail disorder, palmar-plantar erythrodysesthesia syndrome
hud og subkutane væv almindelige: alopeci, akne, tør hud, urticaria, hyperhidrosis ikke almindelige: dermatitis (inklusiv eksem) , akut febril neutrofil dermatosis, fotosensitivitet, pigmenteringsforstyrrelse, panniculitis, hudsår, bulløse tilstande, negleforstyrrelser, palmar-plantar erytrodysæstesisyndrom