Mutations

Mutazione genetica

associated mutations

associate

We evaluated the effects of THBD missense mutations associated with HUS on complement activation by expressing THBD variants in cultured cells

Abbiamo valutato gli effetti delle mutazioni missense THBD associati HUS su attivazione del complemento esprimendo varianti THBD in cellule in coltura

Mutations in the p53 tumour-suppressor gene are the most frequently observed genetic lesions in human cancers. To investigate the role of the p53 gene in mammalian development and tumori- genesis, a null mutation was introduced into the gene by homologous recombination in murine embryonic stem cells. Mice homozygous for the null allele appear normal but are prone to the spontaneous development of a variety of neo- plasms by 6 months of age.

articolo scientifico

Mutate

Mutazione genetica

Mutation

Mutazione genetica

Mutated

Mutazione genetica

Mutator

Mutante

mutation

mutazione NRTI

Mutation

vRNA

Mutation

Mutagene

Mutation

Mutazioni

Mutation

Mutazione

Mutation

Mutante

Mutation

Mutazione puntiforme