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hyperglycemia associates with an increase in free fat acids, which induces cardiac arrhythmias and insulin resistance, causes chemical inactivation of nitric oxide and the production of oxygen reactive species, generating oxidative stress, which produces microvascular and endothelial dysfunction, a prothrombotic state, and vascular inflammation.
a hiperglicemia associa-se ao aumento de ácidos graxos livres, que induzem arritmias cardíacas e resistência insulínica, provoca a inativação química do óxido nítrico e o desencadeamento da produção de espécies reativas de oxigênio, gerando estresse oxidativo, o qual produz disfunção microvascular e endotelial, estado pró-trombótico e inflamação vascular.
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