You searched for: glucuroconjugation [ Turn off colors ]
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Buprenorphine is metabolised by 14-N-dealkylation and glucuroconjugation of the parent molecule and the dealkylated metabolite.
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La buprenorfina se metaboliza por 14-N-desalquilación y por glucuronidoconjugación de la molécula original y del metabolito desalquilado.
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Last Update: 2012-04-10 |
Buprenorphine, when taken orally, undergoes first-pass metabolism with N-dealkylation and glucuroconjugation in the small intestine and the liver.
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En su toma por vía oral, la buprenorfina sufre un metabolismo de primer paso con N-desalquilación y glucuronidoconjugación en el intestino delgado y en el hígado.
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Last Update: 2012-04-10 |
Buprenorphine is eliminated in the faeces by biliary excretion of the glucuroconjugated metabolites (70%), the rest being eliminated in the urine.
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La buprenorfina se elimina en las heces por excreción biliar de los metabolitos glucuronidoconjugados (70%), siendo eliminado el resto por la orina.
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Last Update: 2012-04-10 |
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