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Buprenorphine is metabolised by 14-N-dealkylation and glucuroconjugation of the parent molecule and the dealkylated metabolite.
http://www.emea.europa.eu/

La buprenorfina se metaboliza por 14-N-desalquilación y por glucuronidoconjugación de la molécula original y del metabolito desalquilado.
http://www.emea.europa.eu/

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 3
Quality:

Buprenorphine, when taken orally, undergoes first-pass metabolism with N-dealkylation and glucuroconjugation in the small intestine and the liver.
http://www.emea.europa.eu/

En su toma por vía oral, la buprenorfina sufre un metabolismo de primer paso con N-desalquilación y glucuronidoconjugación en el intestino delgado y en el hígado.
http://www.emea.europa.eu/

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 3
Quality:

Buprenorphine is eliminated in the faeces by biliary excretion of the glucuroconjugated metabolites (70%), the rest being eliminated in the urine.
http://www.emea.europa.eu/

La buprenorfina se elimina en las heces por excreción biliar de los metabolitos glucuronidoconjugados (70%), siendo eliminado el resto por la orina.
http://www.emea.europa.eu/

Last Update: 2012-04-10
Subject: Pharmaceuticals
Usage Frequency: 2
Quality:

Buprenorphine is eliminated in the faeces by biliary excretion of the glucuroconjugated metabolites (70%) , the rest being eliminated in the urine.

24 La buprenorfina se elimina en las heces por excreción biliar de los metabolitos glucuronidoconjugados (70%) , siendo eliminado el resto por la orina.

Last Update: 2008-03-04
Subject: Medical
Usage Frequency: 2
Quality:
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