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QUADRAMET has an affinity for skeletal tissue and concentrates in areas of bone turnover in intimate association with hydroxyapatite; studies in rats have demonstrated that QUADRAMET is cleared rapidly from the blood and localises to growing areas of bone matrix, specifically the layer of osteoid undergoing mineralisation.
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QUADRAMET muestra afinidad por el tejido óseo y se concentra en las zonas de recambio óseo, asociado íntimamente a la hidroxiapatita; los estudios realizados en ratas han puesto de manifiesto que QUADRAMET es aclarado rápidamente de la sangre y se localiza en las zonas de crecimiento de la matriz ósea, más concretamente, en la capa de la sustancia osteoide que sufre mineralización.
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Last Update: 2012-04-10 |
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