Results for hämolymphopoetischen translation from German to English

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hämolymphopoetischen

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in toxizitätsstudien mit mehrfachgabe an ratten und affen, die bis zu 9 monaten dauerten, wurden die hauptsächlichen auswirkungen an folgenden zielorganen festgestellt: dem gastrointestinaltrakt (emesis und diarrhoe bei affen), der nebenniere (stauung und / oder blutung in der nebennierenrinde bei ratten und affen, mit von fibrosen gefolgten nekrosen bei ratten), dem hämolymphopoetischen system (knochenmark-hypozellularität und lymphoider depletion von thymus, milz und den lymphknoten), der bauchspeicheldrüse (azinöse zelldegeneration mit einzelzellnekrose), der speicheldrüse (azinöse hypertrophie), knöchernen verbindungen (verdickung der epiphysenfuge), dem uterus (atrophie) und den ovarien (verminderte follikelreifung).

English

in rat and monkey repeated-dose toxicity studies up to 9-months duration, the primary target organ effects were identified in the gastrointestinal tract (emesis and diarrhoea in monkeys), adrenal gland (cortical congestion and/ or haemorrhage in rats and monkeys, with necrosis followed by fibrosis in rats), haemolymphopoietic system (bone morrow hypocelularity, and lymphoid depletion of thymus, spleen, and lymph node), exocrine pancreas (acinar cell degranulation with single cell necrosis), salivary gland (acinar hypertrophy), bone joint (growth plate thickening), uterus (atrophy) and ovaries (decreased follicular development).

Last Update: 2012-04-10
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